2022 Softball Season Awards
DIVISION I
| First Team All Region | ||||
| # | Year | POS | Player | School |
| 23 | COFr. | C | Kennedy Preston | Indian Hills |
| 20 | Fr. | P | Madie Anderson | Indian Hills |
| 11 | Fr. | P | Ryann Cheek | Indian Hills |
| 7 | Fr. | INF | Destiny Lewis | Indian Hills |
| 22 | Fr. | INF | Sydney Anderson | Indian Hills |
| 5 | COFr. | INF | Breanna Newton | Indian Hills |
| 8 | Fr. | INF | Jael Wilde | Iowa Western |
| 7 | Fr. | INF | Abbi Conrad | Southwestern |
| 12 | COFr. | OF | Gretta Hartz | Indian Hills |
| 2 | Fr. | OF | Karis Gifford | Iowa Western |
| 6 | Fr. | OF | Amayia Hernandez | Iowa Western |
| 6 | So. | OF | Lydia Allen-Barnes | Southeastern |
| 16 | Fr. | DP | Camryn Milley | Iowa Western |
| 15 | Fr. | UTL | Paige Westlin | Marshalltown |
| Second Team All Region | ||||
| # | Year | POS | Player | School |
| 13 | COFr. | C | Alex Beard | Indian Hills |
| 24 | COFr. | P | Madi Huisman | Indian Hills |
| 19 | Fr. | P | Emily Brouse | Iowa Western |
| 6 | COFr. | INF | Bryanna Mehaffy | Indian Hills |
| 13 | Fr. | INF | Olivia Kyes | Iowa Western |
| 13 | Fr. | INF | Emalee Davis | Marshalltown |
| 8 | Fr. | INF | Mady Reed | Southeastern |
| 12 | Fr. | INF | Adessa Brandenberg | Southeastern |
| 29 | So. | INF | Grace Cotton | Southwestern |
| 1 | Fr. | OF | Yanna Roberts | Indian Hills |
| 15 | Fr. | OF | Abbi Cataldo | Indian Hills |
| 1 | So. | OF | Tayler Floyd | Iowa Western |
| 14 | So. | OF | Myla Beckstrom | Iowa Western |
| 17 | Fr. | DP | Kayla Norton | Southeastern |
| 2 | Fr. | UTL | Haley Koch | Southwestern |
Player of the Year: Destiny Lewis, Indian Hills
Pitcher of the Year: Madie Anderson, Indian Hills
Offensive Player of the Year: Sydney Anderson, Indian Hills
Defensive Player of the Year: Jael Wilde, Iowa Western
Coach of the Year: Lindsay Diehl, Indian Hills
DIVISION II
First Team All-Region
| Year | # | School | Name | Pos. |
| So. | 4 | Kirkwood | Peggy Klinger | C |
| So. | 7 | NIACC | Hailey Worman | C |
| So. | 22 | DMACC | Abby Flanagan | P |
| So. | 14 | Iowa Lakes | Lexi Chase | P |
| So. | 1 | Kirkwood | Kori Wedeking | P |
| So. | 2 | DMACC | Sami Miller | IF |
| Fr. | 14 | DMACC | Madison Kearns | IF |
| COSo. | 8 | Ellsworth | Gintare Paskocimaite | IF |
| Fr. | 24 | Iowa Lakes | Bryn Bohmann | IF |
| So. | 22 | Iowa Lakes | Eliya Johnson* | IF |
| So. | 7 | Kirkwood | Emilee Linder | IF |
| Fr. | 15 | DMACC | Kendal Clark | OF |
| So. | 35 | DMACC | Abby Husak | OF |
| Fr. | 5 | Iowa Central | Riley Gilroy | OF |
| Fr. | 3 | Iowa Lakes | Alyssa Thorson* | OF |
| Fr. | 3 | Kirkwood | Grace Lubben | OF |
| So. | 8 | DMACC | Jada Collins | DP |
| Fr. | 7 | DMACC | Emma Dighton | UT |
*At-Large Selections
Second Team All-Region
| Year | # | School | Name | Pos. |
| So. | 2 | Iowa Lakes | Allie McCabe | C |
| So. | 30 | Northeast | Brianna Aguilera | C |
| Fr. | 4 | DMACC | Sydney Kennedy | P |
| So. | 16 | DMACC | Lexi Lander | P |
| So. | 2 | Kirkwood | Payton Akers | P |
| Fr. | 27 | Ellsworth | Lauren Brennan | IF |
| Fr. | 2 | Iowa Central | Amber McKinney | IF |
| So. | 13 | Iowa Central | Loghen Schnetzer | IF |
| Fr. | 21 | Iowa Central | Jori Hajek | IF |
| So. | 7 | Iowa Lakes | Kaitlyn Roundy | IF |
| So. | 4 | Iowa Central | Carlie Thompson | OF |
| Fr. | 6 | Iowa Central | Olivia Harmon | OF |
| So. | 5 | Kirkwood | Alecea Mendoza | OF |
| Fr. | 10 | Kirkwood | Neveah Hildebrant | OF |
| So. | 8 | Kirkwood | Austyn Crees | DP |
| So. | 6 | Kirkwood | Reagan Schutte | UT |
Honorable Mention All-Region
| Year | # | School | Name | Pos. |
| Fr. | 21 | DMACC | Layney Loyd | C |
| So. | 25 | Ellsworth | Maggie Braniff | C |
| So. | 14 | Iowa Central | Mady Lange | C |
| So. | 17 | DMACC | Ellie Jacobson | P |
| Fr. | 17 | Ellsworth | Delaney Vetter | P |
| So. | 15 | Iowa Central | Mackenzie Crampton | P |
| Fr. | 16 | Iowa Central | Olivia Engler | P |
| Fr. | 25 | Iowa Lakes | Mackenna Jones | P |
| Fr. | 12 | Kirkwood | Kara Maiers | P |
| Fr. | 9 | DMACC | Brionna Vasey | IF |
| So. | 10 | DMACC | Delaney Kelley | IF |
| Fr. | 32 | DMACC | Kaylynn Salyars | IF |
| Fr. | 18 | Iowa Central | Sydney Ballard | IF |
| Fr. | 9 | Kirkwood | Annie Gahan | IF |
| So. | 19 | Kirkwood | Kennedy Hill | IF |
| So. | 1 | Northeast | Abby Balfour | IF |
| Fr. | 8 | Northeast | Alexis Folks | IF |
| So. | 18 | Iowa Lakes | Amanda Franke | OF |
| Fr. | 22 | NIACC | Sydney Toman | OF |
| So. | 3 | Northeast | Jade Koch | OF |
| So. | 8 | Northeast | Josie Knust | OF |
| Fr. | 26 | Ellsworth | Neveah Dice | UT |
| So. | 10 | Iowa Central | Mikhaela Muir | UT |
| Fr. | 16 | NIACC | Brianna McPoland | UT |
| Fr. | 9 | Northeast | Emily Spitz | UT |
| So. | 22 | Northeast | Greta Lindberg | UT |
Defensive Player of the Year: Austyn Crees - Kirkwood
Offensive Player of the Year: Emma Eighton - DMACC
Pitcher of the Year: Kori Wedeking - Kirkwood
Coach of the Year: Bob Ligouri, DMACC