DIVISION I
DI 1ST TEAM ALL-REGION
| Position | Name | Class | School | Hometown |
| C | Alexis Westercamp | So. | Indian Hills | Oskaloosa, IA |
| IF | Ashley Rosado | So. | Southeastern | Port St. Luci, FL |
| IF | Tyla Lee | So. | Iowa Western | Red Deer, AB, CAN |
| IF | Sydney Reamer | So. | Iowa Western | West Wendover, NV |
| IF | Chayse Lowney | So. | Southeastern | Fr. Madison, IA |
| IF | Brooke Snider | Fr. | Indian Hills | Rhodes, IA |
| OF | Lily Gregory | So. | Iowa Western | Boise, ID |
| OF | Macey Harrington | Fr. | Indian Hills | Macon, MO |
| OF | Heather Geiger | So. | Southeastern | Burlington, IA |
| OF | Brittini Lloyd | Fr. | Indian Hills | Muscatine, IA |
| P | Alexis Groet | Fr. | Indian Hills | Oskaloosa, IA |
| P | Julie Katz | Fr. | Iowa Western | Louisville, NE |
| UT | Saydee Terrell | So. | Marshalltown | Chariton, IA |
| DP | Chloe Olson | Fr. | Indian Hills | Ankeny, IA |
DI 2ND TEAM ALL-REGION
| Position | Name | Class | School | Hometown |
| C | Cassidy Beeby | Fr. | Iowa Western | McCook, NE |
| IF | Ashley Tennant | Fr. | Marshalltown | Adel, IA |
| IF | Jaylie Reints | So. | Indian Hills | Shell Rock, IA |
| IF | DJ Schmidt | So. | Marshalltown | Des Moines, IA |
| IF | Alyssa Maldonado | So. | Iowa Western | West Covina, CA |
| IF | Vanessa Bakley | So. | Indian Hills | Osceloa, IA |
| OF | Izzy Collins | So. | Southeastern | Ames, IA |
| OF | Carlie Benes | Fr. | Iowa Western | Valparaiso, NE |
| OF | Katie Price | Fr. | Southeastern | Zearing, IA |
| OF | Nicolette Dabbs | So. | Marshalltown | Anchorage, AK |
| P | Lara Pence | Fr. | Southeastern | Carthage, IL |
| P | Nina Hendriks | Fr. | Indian Hills | Utrecht, Netherlands |
| UT | Taylor Pottorff | Fr. | Southeastern | Fort Pierce, FL |
| DP | Jordan Hollon | So. | Indian Hills | Unionville, MO |
Defensive Player of the Year: Brittini Lloyd, Indian Hills
Pitcher of the Year: Alexis Groet, Indian Hills
Offensive Player of the Year: Lily Gregory, Iowa Western
Coach of the Year: Lindsey Diehl, Indian Hills
Player of the Year: Brooke Snider, Indian Hills
DIVISION II
First Team All-Region
| Year | # | School | Name | Pos. |
| Fr. | 3 | NIACC | Hannah Faktor | C |
| Fr. | 8 | Southwestern | Kaitlyn Schad | C |
| Fr. | 10 | DMACC | Josie Swafford | P |
| Fr. | 16 | Kirkwood | Erin Hocker | P |
| Fr. | 12 | NIACC | Kristen Peka | P |
| So. | 12 | DMACC | Mia Ruther | INF |
| So. | 3 | DMACC | Avery Guy | INF |
| Fr. | 16 | Iowa Central | Sophia Cave | INF |
| So. | 12 | Kirkwood | Rachel Stewart | INF |
| Fr. | 7 | Kirkwood | London Jackson* | INF |
| So. | 22 | NIACC | Alyssa Laxson* | INF |
| So. | 21 | NIACC | Kaci Sherwood | INF |
| Fr. | 6 | DMACC | Morgan Lewis | OF |
| So. | 7 | DMACC | Kaisha Wells* | OF |
| So. | 18 | Iowa Central | Cheyenne Andersen | OF |
| So. | 7 | Iowa Lakes | Taylor Allen | OF |
| Fr. | 4 | Kirkwood | Shelby Hulsebus | OF |
| Fr. | 1 | DMACC | Ally Pickering | DP |
| Fr. | 23 | Iowa Central | Bre Tjebben | UTL |
| So. | 21 | Iowa Lakes | Yasmine Nix | UTL |
Second Team All-Region
| Year | # | School | Name | Pos. |
| Fr. | 15 | DMACC | Elly Schuemann | C |
| So. | 3 | Iowa Central | Payton Adwell | C |
| Fr. | 24 | Northeast | Maggie Berryman | C |
| Fr. | 4 | DMACC | Dana Dunbar | P |
| Fr. | 22 | Kirkwood | Bradee Bouman | P |
| Fr. | 16 | NIACC | Kylie Sherwood | P |
| Fr. | 8 | DMACC | Maddie Karr | INF |
| So. | 5 | DMACC | Ellie Dixon | INF |
| Fr. | 8 | Iowa Central | Parker Matthews | INF |
| Fr. | 1 | Kirkwood | Jayme Finn | INF |
| So. | 18 | NIACC | Marissa Norby | INF |
| So. | 20 | DMACC | Jayci Vos | OF |
| Fr. | 19 | Iowa Central | Gabi Bingham | OF |
| Fr. | 15 | Kirkwood | Randyn Carter | OF |
| So. | 17 | NIACC | Kaitlyn Carlson | OF |
| So. | 8 | Kirkwood | Lauren Klaahsen | DP |
| Fr. | 5 | Kirkwood | Autum Barthelman | UTL |
Honorable Mention All-Region
| Year | # | School | Name | Pos. |
| So. | 5 | DMACC | Katelin Schumacher | C |
| So. | 10 | Iowa Lakes | Laurie Custard | C |
| Fr. | 14 | NIACC | Ciana Sonberg | C |
| Fr. | 21 | DMACC | Ally Anderson | P |
| Fr. | 19 | DMACC | Peyton Parker | P |
| So. | 22 | Ellsworth | Hannah Hoffman | P |
| Fr. | 34 | Iowa Central | Bre Small | P |
| So. | 17 | Iowa Central | Kallie Malloy | P |
| So. | 21 | Iowa Central | Alex Boyce | P |
| So. | 9 | Iowa Central | Jenna Peschel | INF |
| Fr. | 14 | Iowa Central | Payton Andersen | INF |
| So. | 8 | Ellsworth | Lexi Riggall | INF |
| So. | 4 | Iowa Lakes | Kacie Salazar | INF |
| Fr. | 1 | NIACC | Tayler Schmidt | INF |
| Fr. | 1 | Northeast | Sydney Kelley | INF |
| So. | 5 | Northeast | Rosario Garcia | INF |
| Fr. | 23 | Southwestern | Ali Enright | INF |
| Fr. | 13 | Southwestern | Ella Rutherford | INF |
| Fr. | 7 | Ellsworth | Kylie Adden | OF |
| Fr. | 15 | Ellsworth | Gwen Hovorka | OF |
| So. | 14 | Iowa Lakes | Gabby Heckard | OF |
| Fr. | 5 | Iowa Lakes | Madisyn Arechedrra | OF |
| Fr. | 1 | Iowa Lakes | Lexus Gorospe | OF |
| Fr. | 20 | Northeast | Jacqueline Denning | OF |
| So. | 2 | Southwestern | Klarissa McElroy | OF |
| So. | 14 | Kirkwood | Lauren Kuch | UTL |
| Fr. | 6 | NIACC | Morgan Kelley | UTL |
| Fr. | 9 | Northeast | Madison McKewon | UTL |
| Fr. | 3 | Ellsworth | Katie Smith | UTL |
Defensive Player of the Year: Rachel Stewart, Kirkwood
Offensive Player of the Year: Mia Ruther, DMACC
Pitcher of the Year: Josie Swafford, DMACC
Coach of the Year: Bob Ligouri, DMACC