Division I
1st Team All-Region
| Position | Name | School |
| INF | Lizzy Tucker | Indian Hills |
| C | Angela Jay | Iowa Western |
| INF | Bradi Wall | Iowa Western |
| P | Stephanie Schmidt | Iowa Western |
| P | Ashley Wailand | Muscatine |
| INF | Kayli Schurman | Muscatine |
| INF | Kelli Shimp | Muscatine |
| OF | Amy Harner | Southeastern |
| P | Haley Baker | Southeastern |
| INF | Hannah Pauly | Southeastern |
| INF | Mayles Rodriguez | Southeastern |
| C | Milagros Lozada | Southeastern |
2nd Team All-Region
| Position | Name | School |
| OF | Kris Penick | Indian Hills |
| OF | Toby Beaver | Indian Hills |
| INF | Brooke Cronican | Iowa Western |
| OF | Julie Santillanes | Iowa Western |
| INF | Luisa Bar | Iowa Western |
| INF | Courtney Poling | Muscatine |
| P | Jami Whitcomb | Muscatine |
| INF | Sam Saladino | Muscatine |
| INF | Amanda Ricker | Southeastern |
| OF | Kelley Bettag | Southeastern |
| P | Libby Helt | Southeastern |
| P | Machelle Rowan | Southeastern |
Division II
1st Team All-Region
| Position | Name | School |
| INF | Brittany Martin | Iowa Central |
| C | Lexy Rozmus | Iowa Central |
| INF | Steph Graziani | Iowa Central |
| OF | Adrianna Tabone | Iowa Lakes |
| C | Ashley Heiberger | Iowa Lakes |
| UTL | Christianne Saiz | Iowa Lakes |
| OF | Christy Cabrera | Iowa Lakes |
| P | Julia Nealer | Iowa Lakes |
| DH | Pricilla Quintana | Iowa Lakes |
| P | Amanda Lambrecht | Kirkwood |
| OF | Carlie Schnoebelen | Kirkwood |
| INF | Jami Miller | Kirkwood |
| INF | Jamie Davis | Kirkwood |
| P | Kylee Knop | Kirkwood |
| INF | Molly Link | Kirkwood |
| OF | Jordan Vaske | NIACC |
2nd Team All-Region
| Position | Name | School |
| C | Callie Henry | Ellsworth |
| OF | Josi Van Houten | Ellsworth |
| OF | Ashley Willard | Iowa Central |
| P | Christina Bradley | Iowa Central |
| INF | Lara Reese | Iowa Central |
| P | Nicole Danna | Iowa Central |
| INF | Staci Ritchey | Iowa Central |
| INF | Kristen Heimerl | Iowa Lakes |
| OF | Melissa Lenzi | Iowa Lakes |
| C | Chelsea Parrish | Kirkwood |
| INF | Melissa Walls | Kirkwood |
| P | Ashley Allen | Marshalltown |
| INF | Cayla Collins | Marshalltown |
| UTL | Amanda Speake | NIACC |
| DH | Katie Tew | Southwestern |
| OF | Nikkie Vreeland | Southwestern |
3rd Team All-Region
| Position | Name | School |
| P | Cari Mergen | Ellsworth |
| INF | Kaitlin Miller | Ellsworth |
| INF | Makanai Scarlett | Ellsworth |
| OF | Brittany Stout | Iowa Central |
| INF | Courtney Vaughn | Iowa Central |
| C | Kenzie Scharf | Iowa Central |
| OF | Missy Ulmer | Iowa Central |
| OF | Shelby Feldt | Iowa Central |
| INF | Julia Rubek | Iowa Lakes |
| OF | Morgan Davis | Iowa Lakes |
| OF | Brandee Bohr | Kirkwood |
| P | Shelby Dougherty | Kirkwood |
| UTL | Erin Davitt | Marshalltown |
| OF | Jenna Baker | Marshalltown |
| INF | Kayla Blocker | Marshalltown |
| UTL | Sami Stogdill | Marshalltown |
| INF | Alicia Martin | NIACC |
| P | Bree Giordana | NIACC |
| P | Laci Pustina | NIACC |
| INF | Amber Brown | Southwestern |
| INF | Becky Anderson | Southwestern |
| UTL | Cassie Kadel | Southwestern |