1st Team All-Region
| Position | Name | Class | School |
| CB | CJ Jones | SO | Ellsworth |
| LB | Corey Reed | SO | Ellsworth |
| WR | Gerald Reed | SO | Ellsworth |
| SS | James Jones | SO | Ellsworth |
| OL | Janssen Hayes | SO | Ellsworth |
| OL | Brad Claytor | SO | Iowa Central |
| K | Brandon Burden | SO | Iowa Central |
| LB | Bryce Leggins | SO | Iowa Central |
| LB | Curtis Meier | SO | Iowa Central |
| CB | Darrell Lloyd | SO | Iowa Central |
| WR | Donte Shackelford | SO | Iowa Central |
| DE | Kyle Wiuff | SO | Iowa Central |
| RB | Steve Harper | SO | Iowa Central |
| CB | Anton Cullom | SO | NIACC |
| QB | Ben Alford | SO | NIACC |
| LB | De'Veon Harris | SO | NIACC |
| DL | Jeremy Robertson | SO | NIACC |
| OL | Nick Daly | SO | NIACC |
| RB | Tommy Bryant | SO | NIACC |
| OL | Blake Ogletree | SO | North Dakota |
| RB | Brian McNeil | SO | North Dakota |
| OL | David Booettcher | SO | North Dakota |
| OL | Zach Condon | SO | North Dakota |
All-Region Honorable Mention
| Position | Name | Class | School |
| FS | Adam Behrends | SO | Ellsworth |
| LB | Brandon Dorsett | SO | Ellsworth |
| CB | Chris Miller | SO | Ellsworth |
| OL | Curtis Thommen | SO | Ellsworth |
| WR | Dexter Baldwin | SO | Ellsworth |
| QB | Ian Gilworth | SO | Ellsworth |
| DE | JJ Henderson | FR | Ellsworth |
| TE | Luke Brocka | FR | Ellsworth |
| FB | Tyler Pacha | SO | Ellsworth |
| DE | Zach Wilson | SO | Ellsworth |
| OL | Blake Rowland | SO | Iowa Central |
| DL | Caleb Tyler | SO | Iowa Central |
| DE | Jimmy Fennesy | SO | Iowa Central |
| LB | Joe Cason | FR | Iowa Central |
| WR | Joel Hanson | SO | Iowa Central |
| OL | Mike Manternach | FR | Iowa Central |
| TE | Nick Grobe | SO | Iowa Central |
| DL | Robert Austin | SO | Iowa Central |
| OL | Spenser Jeshani | FR | Iowa Central |
| RB | Travis Rhone | SO | Iowa Central |
| LB | Will Brown | FR | Iowa Central |
| QB | Zach Edwards | FR | Iowa Central |
| LB | Zach Mason | SO | Iowa Central |
| LB | Chris Tejeda | SO | NIACC |
| SS | Corey Robertson | FR | NIACC |
| FS | Devorian Burns | SO | NIACC |
| DL | Donny Severs | SO | NIACC |
| WR | Jesse Kent | SO | NIACC |
| OL | Karl Robertson | SO | NIACC |
| OL | Kyle Staudt | FR | NIACC |
| LB | Matt Weberpal | SO | NIACC |
| DL | Reggie St. Pierre | FR | NIACC |
| WR | Tim Richmond | FR | NIACC |
| OL | Trent Flander | SO | NIACC |
| DE | Brad Albano | FR | North Dakota |
| DB | Dalton Outlaw | SO | North Dakota |
| DB | Gyangelo Bradden | SO | North Dakota |
| LB | Shane Roach | SO | North Dakota |