1st Team All-Region
| Position | Name | Class | School |
| LB | Cody Stockdale | SO | Ellsworth |
| DE | Onesi Lino | SO | Ellsworth |
| WR | TJ Edwards | SO | Ellsworth |
| DL | Albert Rodriguez | SO | Iowa Central |
| RB | Darian Williams | SO | Iowa Central |
| WR | Donte Shackleford | FR | Iowa Central |
| TE | Jeremy Joynt | SO | Iowa Central |
| OL | Joe Hudgins | SO | Iowa Central |
| QB | Jordan Frain | SO | Iowa Central |
| DB | Will Lewis | FR | Iowa Central |
| DE | Eric Young | SO | NIACC |
| DB | Juan Martin | SO | NIACC |
| RB | Kevin Hart | SO | NIACC |
| OL | Kyle Dunn | SO | NIACC |
| LB | Mike Liggins | FR | NIACC |
| OL | Graham Adams | SO | North Dakota |
| RB | Jerome Messam | FR | North Dakota |
| DB | John West | SO | North Dakota |
| DB | Justin Brown | SO | North Dakota |
| DL | Mike Brown | SO | North Dakota |
| LB | Will Kassulker | SO | North Dakota |
All-Region Honorable Mention
| Position | Name | Class | School |
| WR | Chris Beekman | SO | Ellsworth |
| DB | CJ Jones | FR | Ellsworth |
| LB | Jason Chambers | SO | Ellsworth |
| RB | Marcus Dawson | SO | Ellsworth |
| DB | Monroe Tillman | SO | Ellsworth |
| LB | Siasosi Lino | FR | Ellsworth |
| QB | Zach Thomas | SO | Ellsworth |
| DL | Ben Schhumacher | SO | Iowa Central |
| OL | Bill Speiser | SO | Iowa Central |
| OL | Blake Rowland | FR | Iowa Central |
| OL | Brad Claytor | FR | Iowa Central |
| DL | Caleb Taylor | FR | Iowa Central |
| DL | Jimmy Fennesy | FR | Iowa Central |
| DB | Mack Kimble | SO | Iowa Central |
| RB | Steven Harper | FR | Iowa Central |
| DB | Tanner Sulzberger | SO | Iowa Central |
| LB | Zach Wilker | SO | Iowa Central |
| LB | Chris Tejada | FR | NIACC |
| DB | Derrick Holmes | FR | NIACC |
| DL | Glendon Klein | SO | NIACC |
| DL | Jeremy Robertson | FR | NIACC |
| DB | Josh Rose | SO | NIACC |
| OL | Karl Robertson | FR | NIACC |
| LB | Alec Gullickson | FR | North Dakota |
| OL | Blake Ogletree | FR | North Dakota |
| WR | Dario Moore | FR | North Dakota |
| WR/DB | Darren Suggs | FR | North Dakota |
| WR | Emanuel Baker | SO | North Dakota |
| QB | Josh Kreutner | SO | North Dakota |
| DL | Mike Bartels | FR | North Dakota |
| OL | Rafael Silva | SO | North Dakota |
| DL | Ryan Pentimalli | SO | North Dakota |
| OL | Zach Condon | FR | North Dakota |