1st Team All-Region
| Position | Name | Class | School |
| DL | Aaron Johnson | SO | Ellsworth |
| DL | Adam Hughes | FR | Ellsworth |
| LB | James Dotson | SO | Ellsworth |
| CB | Terrence Jones | SO | Ellsworth |
| RB | Cory Mack | SO | Iowa Central |
| LB | Danny Triplett | SO | Iowa Central |
| CB | David Daniels | SO | Iowa Central |
| LB | Gabe Toomey | SO | Iowa Central |
| OL | Luke Stigler | SO | Iowa Central |
| DL | Robert Savitsky | SO | Iowa Central |
| QB | Steve Rush | SO | Iowa Central |
| LB | Craig Edwards | SO | NIACC |
| FB | Donnie Harris | SO | NIACC |
| OL | Gabe Vargas | SO | NIACC |
| DL | Jirey Siner | SO | NIACC |
| QB | Mike Lawrence | SO | NIACC |
| RB | Robert Anderson | SO | NIACC |
| DL | Keith Lipka | SO | North Dakota |
| DL | Mike Draper | SO | North Dakota |
| LB | Mitch Botnen | SO | North Dakota |
| WR | Neuby Ras | SO | North Dakota |
| K | Pete Schletz | SO | North Dakota |
| RB | Quitman Kyles | FR | North Dakota |
| OL | Ben Hogan | SO | Waldorf |
| DB | Gary Eichenberger | SO | Waldorf |
| OL | Kody Wenndt | SO | Waldorf |
All-Region Honorable Mention
| Position | Name | Class | School |
| LB | Erskine Jude | SO | Ellsworth |
| RB | Essic Sanders | SO | Ellsworth |
| WR | Frankie Jenkins | SO | Ellsworth |
| DE | Jamall Simpson | SO | Ellsworth |
| OL | Jeremy Hoffpauir | FR | Ellsworth |
| DE | Matt Rodemeyer | FR | Ellsworth |
| WR | Nathan Oberender | SO | Ellsworth |
| LB | Tanner Varner | FR | Ellsworth |
| S | Ben Spellman | SO | Iowa Central |
| S | James Idleburgh | SO | Iowa Central |
| OL | Jarred Verge | SO | Iowa Central |
| TE | Justin Mohr | SO | Iowa Central |
| P | Justin Porter | SO | Iowa Central |
| FB | Reggie Brown | SO | Iowa Central |
| DL | Robert Taylor | SO | Iowa Central |
| DL | Steve Wegner | FR | Iowa Central |
| OL | Todd Rodgers | SO | Iowa Central |
| LB | Vahn Schumacher | SO | Iowa Central |
| OL | Adam Peterson | SO | NIACC |
| DL | Andre Gould | FR | NIACC |
| RB | BJ Flowers | FR | NIACC |
| OL | Groshawn Edwards | FR | NIACC |
| DL | Jermyah Graves | FR | NiACC |
| OL | Jordan Rasberry | SO | NIACC |
| LB | Josh Pesek | SO | NiACC |
| LB | Nate Geerts | FR | NiACC |
| LB | Andy Spells | FR | North Dakota |
| DB | Brian Dixon | FR | North Dakota |
| DB | DeGeorge Tebbs | FR | North Dakota |
| TE | Kurt Sand | SO | North Dakota |
| LB | Corey Goodhue | SO | Waldorf |
| K | Dustin Schmelzle | FR | Waldorf |
| RB | Justin Ashford | FR | Waldorf |
| LB | Lee Schissel | SO | Waldorf |
| LB | Ryan Swanson | SO | Waldorf |
| WR | Scott Gaskill | SO | Waldorf |